? Bone Marrow-Derived MSC Therapy
Powerful Healing from Within Your Own Bones
What Are Bone Marrow-Derived Medicinal Signaling Cells?
Bone marrow is a rich source of Medicinal Signaling Cells (MSCs)—special cells that have the ability to act as repair coordinators for cartilage, muscle, tendon, or bone. These cells also healing signals that reduce inflammation and encourage damaged tissue to repair itself¹.
This therapy involves collecting a small amount of bone marrow from the back of your pelvis, concentrating the Medicinal Signaling Cells, and injecting them into the area that needs healing—like a damaged joint or disc.
How the Procedure Works
- Bone Marrow Aspiration: Using local anesthetic, a trained provider extracts bone marrow from your pelvic bone with a specialized needle.
- Processing: The sample is spun in a high-speed centrifuge to separate and concentrate the medicinal signaling cells.
- Targeted Injection: The medicinal signaling cells are then injected precisely into the affected area, often under ultrasound or fluoroscopic guidance.
Once injected, these cells go to work restoring balance and promoting healing in the injured tissue².
Conditions Treated with Bone Marrow Medicinal Signaling Cells (MSCs)
At Johnson Medical Center, we use bone marrow-derived medicinal signaling cells to help patients with:
- Advanced joint arthritis (knee, hip, shoulder)
- Disc degeneration in the spine
- Non-healing bone fractures
- Chronic tendon injuries
- Sports injuries that haven’t responded to rest or therapy
This therapy is especially valuable for middle age patients or those with more severe wear-and-tear injuries.
How Does This Compare to Adipose Stem Cells?
While both types of cell therapies are effective, bone marrow-derived cells may be better suited for more advanced degeneration or complex orthopedic cases. Bone marrow contains a higher concentration of hematopoietic (blood-forming) cells and immune-modulating factors, which can play a role in healing chronic inflammation or immune-driven joint degeneration³.
That said, bone marrow aspiration may result in temporary soreness at the donor site. It’s a tradeoff—but often worth it for patients with advanced conditions.
A Natural, Personalized Solution
Since these medicinal signaling cells come from your own body, the treatment is autologous and biocompatible—minimizing risks and maximizing outcomes. Most patients experience gradual improvement in pain, function, and range of motion over the weeks and months following treatment.
Bone marrowmedicinal signaling cell therapy is a minimally invasive, drug-free option for people who want to avoid surgery or long-term medications.
? Sources
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430914/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292164/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769108/
Regulatory Information
Johnson Medical Center is fully committed to complying with all Florida state and FDA regulations. Our MSC therapies are offered under approved protocols to ensure patient safety and regulatory adherence.
Before treatment, our patients receive detailed information about the investigational nature of MSC therapies, including potential risks and benefits, as required by Florida law. We are committed to ensuring you make an informed decision about your care.
Our umbilical cord-derived MSC therapies are processed in facilities that comply with FDA’s current Good Manufacturing Practices (cGMP) and Florida state regulations, ensuring the highest standards of safety and quality.
The mesenchymal signaling cell (MSC) therapies offered at Johnson Medical Center are investigational and not currently approved by the U.S. Food and Drug Administration (FDA) for the treatment of arthritic joint conditions or soft tissue injuries. These therapies are provided under an FDA-approved clinical trial or expanded access program. Patients should be aware that experimental treatments carry risks, including infection or lack of efficacy, and should discuss these with their healthcare provider. To report any adverse events, please contact the FDA’s MedWatch program at www.fda.gov/medwatch or 1-800-FDA-0178.
In compliance with Florida law, Johnson Medical Center informs patients that our mesenchymal signaling cell (MSC) therapies are not approved by the FDA for the treatment of arthritic joint conditions or soft tissue injuries. Our clinic is registered with the Florida Department of Health, lab adheres to FDA manufacturing standards, and undergoes annual state inspections. During the informed consent process, we provide detailed information about the investigational nature of these therapies, including potential risks and benefits.