Harness the Power of Medicinal Signaling Cells for Healing

Restore Your Body’s Natural Healing Potential

At Johnson Medical Center, we’re dedicated to helping you reclaim your mobility and live pain-free, even as you age. Our innovative therapies harness the extraordinary power of medicinal signaling cells (MSCs)—nature’s master coordinators of tissue repair—to treat arthritic joint conditions and soft tissue injuries. Guided by decades of research and the pioneering work of Dr. Arnold Caplan, our treatments offer a promising path to lasting relief and renewed vitality.

Why Healing Slows with Age

As we age, our body’s ability to heal from injuries or chronic conditions diminishes. In our youth, cuts and fractures mend swiftly, often leaving little trace. But by our 40s, 50s, and beyond, healing slows, leading to persistent pain, stiffness, or limited movement. What causes this decline?

  • Declining MSC Potency: Medicinal signaling cells (MSCs) are most abundant and potent at birth, orchestrating rapid tissue repair. As we age, their concentration and ability to replicate decrease, reducing our regenerative capacity.
  • Immune System Changes: The immune system is a key contributor to healing, managing inflammation and coordinating repair. However, it works alongside other cellular and molecular mechanisms, including MSCs, which also weaken with age.
  • Reduced Repair Signals: Over time, the body produces fewer signals to stimulate tissue regeneration, resulting in slower recovery and more scar tissue.

At Johnson Medical Center, we address these challenges with cutting-edge MSC therapies, designed to restore your body’s natural healing power.

Declining MSC in humans with age.

Declining MSC in humans with age.
Johnson Medical Center

What Are Medicinal Signaling Cells (MSCs)?

Medicinal signaling cells (MSCs)

MSCs act as repair coordinators – Johnson Medical Center

You may have heard of “stem cells,” but the cells we use are more accurately called medicinal signaling cells (MSCs). Here’s what makes them unique:

  • A Breakthrough Discovery: Dr. Arnold Caplan significantly advanced the characterization and therapeutic application of MSCs in the late 1980s, initially naming them “mesenchymal stem cells.” He later recognized that their primary role is not to become new tissue but to signal other cells to repair and regenerate. In 2017, he proposed renaming them “medicinal signaling cells” to reflect this function.
  • How MSCs Work: Unlike true stem cells (e.g., embryonic or tissue-specific stem cells) that differentiate into specific tissues, MSCs act as repair coordinators. They travel through blood vessels to injury sites, detect damage signals, and respond by releasing biologically active factors (e.g., growth factors, cytokines, exosomes) that:
    • Reduce inflammation
    • Recruit repair cells
    • Stimulate tissue regeneration
  • Creating a Healing Environment: By fostering an optimal environment for repair, MSCs help your body heal itself, making them ideal for conditions like arthritis and soft tissue injuries.

The Power of Umbilical Cord Tissue

The most potent MSCs are found at birth, particularly in umbilical cord tissue (Wharton’s jelly). These young, vibrant cells are at their peak, unaffected by aging or disease, and are typically discarded after birth. At Johnson Medical Center, we transform this ethical and abundant resource into life-changing therapies.

The Umbilical Cord showing the Wharton's Jelly, one vein and two arteries.

Wharton’s jelly, a gelatinous substance within the umbilical cord and contains many healing tissues.

Our Approach: Combining MSCs with Physical Medicine

At Johnson Medical Center, we believe in a comprehensive approach to healing. Based on emerging evidence and our practice’s expertise, we combine umbilical cord-derived MSC therapies with physical medicine (e.g., physiotherapy, rehabilitation) to maximize your recovery.

Here’s how it works:

  • Precision MSC Therapy: We deliver MSCs via targeted injections into affected joints or tissues, where they detect injury signals and release factors to reduce inflammation, repair cartilage, and regenerate tissue.
  • Physical Medicine: Our personalized rehabilitation programs enhance MSC effectiveness, improve joint mobility, and strengthen supporting muscles, helping you return to your active lifestyle.
  • Conditions We Treat:
    • Arthritic Joint Conditions: MSCs show promise in alleviating pain and improving function in osteoarthritis by promoting cartilage regeneration and reducing inflammation.
    • Soft Tissue Injuries: From tendonitis to ligament tears, MSCs support faster recovery and better tissue repair.
    • Neck, Back, Shoulders, Hips, Knees, others.

Why Choose Johnson Medical Center?

  • Expertise: Our team is trained in the latest regenerative medicine techniques, building on the foundational work of Dr. Arnold Caplan and current research.
  • Safety and Quality: We use ethically sourced, high-quality umbilical cord MSCs, processed under strict regulatory standards.
  • Personalized Care: Every patient receives a tailored treatment plan, combining MSC therapy with physical medicine for optimal results.

Commitment to Results: Our patients report reduced pain, improved mobility, and a better quality of life, supported by emerging scientific evidence.

Staff at Johnson Medical Center

Take the First Step Toward Healing

Don’t let pain or limited mobility define your life. At Johnson Medical Center, we’re harnessing the power of medicinal signaling cells to help you heal naturally and rediscover the joy of movement. Contact us today to schedule a consultation and learn how our therapies can work for you.

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Regulatory Information

Johnson Medical Center is fully committed to complying with all Florida state and FDA regulations. Our MSC therapies are offered under approved protocols to ensure patient safety and regulatory adherence.

Before treatment, our patients receive detailed information about the investigational nature of MSC therapies, including potential risks and benefits, as required by Florida law. We are committed to ensuring you make an informed decision about your care.

Our umbilical cord-derived MSC therapies are processed in facilities that comply with FDA’s current Good Manufacturing Practices (cGMP) and Florida state regulations, ensuring the highest standards of safety and quality.

The mesenchymal signaling cell (MSC) therapies offered at Johnson Medical Center are investigational and not currently approved by the U.S. Food and Drug Administration (FDA) for the treatment of arthritic joint conditions or soft tissue injuries. These therapies are provided under an FDA-approved clinical trial or expanded access program. Patients should be aware that experimental treatments carry risks, including infection or lack of efficacy, and should discuss these with their healthcare provider. To report any adverse events, please contact the FDA’s MedWatch program at www.fda.gov/medwatch or 1-800-FDA-0178.

In compliance with Florida law, Johnson Medical Center informs patients that our mesenchymal signaling cell (MSC) therapies are not approved by the FDA for the treatment of arthritic joint conditions or soft tissue injuries. Our clinic is registered with the Florida Department of Health, lab adheres to FDA manufacturing standards, and undergoes annual state inspections. During the informed consent process, we provide detailed information about the investigational nature of these therapies, including potential risks and benefits.

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